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Infectious Disease
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Focus On: Dalbavancin A novel long-acting lipoglycopeptide antibiotic

Dalbavancin (Pfizer) is a new lipoglycopeptide antibiotic in phase 3 trials for the treatment of resistant gram-positive pathogens including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). This agent exerts its bactericidal activity by binding to the terminal D-alanyl-D-alanine moiety of peptidoglycan precursors, thus blocking enzymes involved in the final stages of peptidoglycan synthesis and cell wall formation. Peak concentrations of dalbavancin occur immediately following infusion and increase in proportion to the dose given.
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Featured Wire Releases What's this?
11-6-07 17:32 ET
New Physician Resource for Practice Management, Clinical Decision Support and Patient Care
Features

Sexually transmitted infections: Fighting non-viral STIs

Michelle is a healthy appearing, athletic 16-year-old who presents to the clinic with a 4-day history of itching "down there" and smelly discharge. During the intake, completed while her mother was present, Michelle vehemently denied that she has ever done "anything more than make out." However...
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HIV screening urged for high-risk adults

The U.S. Preventive Services Task Force (USPSTF) strongly advises physicians to screen all adults at high risk for human immunodeficiency virus (HIV). This recommendation is one of several primary clinical recommendations recently released from the USPSTF.
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Contemporary Management of Urosepsis: Updated Critical Care Guidelines

A urinary tract infection (UTI) that spreads into the systemic circulation—urosepsis—is a life-threatening condition that requires emergent treatment. Rigors, high fevers, mental status changes, hypotension, tachycardia, and tachypnea are characteristic (1). When patients present with or develop these symptoms, it is critical to promptly initiate IV fluids, obtain cultures, and administer broad-spectrum antibiotics.
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Active education helps prevent antibiotic misuse

Reducing excessive or inappropriate antibiotic use is the best way to slow down the spread of antimicrobial resistance in bacterial infections. A report examining dozens of studies of quality-improvement (QI) interventions found that actively engaging the clinician in workshops or educational outreach on antibiotic treatment appears to be more effective than simply posting signs about correct/incorrect antibiotic use. However, most QI interventions are generally effective at reducing both inappropriate antibiotic selection and treatment.
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Industry Roundup

Gastric acid-suppressive drugs linked to C difficile infection

 


This shot targets those exposed to hepatitis B

 


Physicians warm of overuse of vancomycin in treating hospital-acquired pneumonia

 


MRSA challenges dermatologists

 
Wire Releases What's this?
September 2008
 
9-4-08 11:38 ET

Live Endoscopic Sympathectomy

November 2007
 
11-6-07 17:32 ET

New Physician Resource for Practice Management, Clinical Decision Support and Patient Care

August 2006
 
8-24-06 12:03 ET

2005 Medical Group Data Finds Financial Losses, Despite Increases in Physician Compensation for Most Specialties

April 2006
 
4-27-06 14:45 ET

Pharmacy Benefit Management Institute Recognizes Innovation in Drug Benefit Industry

March 2006
 
3-29-06 16:23 ET

MerckMedicus™ Provides Online and Wireless Access to Medical Resources With No Access Fees

3-23-06 8:52 ET
Skyscape Launches Harriet Lane Handbook With Exclusive New Tools For Point of Care Decision-Support -- Featured at NAPNAP, booth #1213 --
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> HIV & AIDS

 
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